El carninoma oral felino de células escamosas es un tipo de cáncer que suele tener un mal pronóstico debido a que, habitualmente, se diagnostica cuando el problema está ya muy avanzado. Una fundación estadounidense está financiando cuatro líneas de investigación para combatirlo.
El cáncer oral es una enfermedad muy grave y relativamente frecuente en gatos sénior. El tumor más común es el carcinoma de células escamosas y suele tener un pronóstico muy malo debido a que los animales son llevados al veterinario cuando el cáncer ya está en un estado avanzado y no va a responder bien al tratamiento.
La Morris Animal Foundation está financiando en Estados Unidos cuatro líneas de investigación sobre el carcinoma oral felino de células escamosas, según informa en su blog.
Susan M. LaRue, de la Colorado State University, está comprobando la eficacia de la radiación estereotáctica, una nueva terapia que consiste en irradiar a los pacientes con dosis de radiación más altas de lo habitual pero por tiempos más breves. De esta forma se consigue que la terapia se centre más eficazmente en los tejidos cancerosos, reduciéndose así los efectos secundarios y mejorando la calidad de vida de los gatos durante el tratamiento.
En la Tufts University, los doctores Elizabeth A. McNiel y Kevin Mayo investigan cómo cortar el suministro sanguíneo del tumor. Tratan de encontrar la forma de inhibir la creación de vasos sanguíneos que aporten nutrientes al tejido canceroso y destruir los que ya lo estén haciendo. Mayo ha diseñado una proteína que destruye las células endoteliales de los vasos sanguíneos y están probando su eficacia.
William C. Kisseberth lidera un equipo de la Ohio State University que ha investigado un nuevo tipo de medicamentos anticancerosos, los inhibidores de la histona deacetilasa, para combatir el cáncer oral en gatos. En ratones y personas ya se ha comprobado que actúan inhibiendo el crecimiento tumoral, pero son necesarios más estudios clínicos para ver la actividad de este producto en felinos.
Y el cuarto estudio también se está desarrollando en la Ohio State University, por parte de Smitha Pillai y Thomas Rosol, que están investigando diferentes alternativas para prevenir la destrucción ósea que produce el carcinoma oral, cuyas consecuencias son pérdida de piezas dentales, infección del hueso y dolor intenso. Han observado que la combinación de inhibidores de la resorción ósea con antineoplásicos tiene un efecto positivo. Por Joaquín Ventura García PVArgos
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martes, 3 de enero de 2012
Dr. Mahaney’s Musings on Bugsy Wonderdog’s Textual Mutterings in Educating Humans
Few dogs can express their intellectual capacity in a manner that will produce a piece of written work. Bugsy, a Goldendoodle who served as a constant companion to his family and as the brand mascot for Lucky Dog Cuisine (LDC), was one of those special dogs.
Although Bugsy passed away in 2011, his message lives on through Educating Humans on life from a dog’s point of view, an endearing and amusing collection of life lessons for other dogs and their care-taking humans.
Here are a few of my favorites.
On Car Rides
Bugsy holds the popular canine perspective that car rides are great, since "we [dogs] never know where we are going." Even if the trip’s destination is the veterinarian’s office, the ride is likely reminiscent of other outings until the final turn into the hospital’s parking lot.
As modern life is scheduled with numerous responsibilities dictating every waking moment, I appreciate Bugsy’s openness to uncertainty. The simpler existence most dogs lead permits the outlook that each experience is novel and potentially rewarding.
As part of my efforts to live more simply in 2012, I am striving to embody Bugsy’s positive perspective. I’ll start by taking more spontaneous car outings to the adventuresome places enjoyed by my dog, Cardiff. Perhaps a new beach or hiking trail will serve as our uncharted destination.
On Training
Bugsy hails the merits of early, consistent, and positive reinforcement based training. I agree with and embody Bugsy’s directives with Cardiff well into his adulthood. After all, good behavior strengthens the bond between humans and their canine companions.
Bugsy also notes dogs' ability to direct human behaviors typically benefitting dogs' desires. "When I pace back and forth at 5:30, you know it is dinnertime" is reminiscent of Cardiff’s habit of strategically placing a paw onto the person responsible for provision of his food.
On Computers
Bugsy shows remarkable dedication to writing "while [his] peers are all fetching, running in the park, and peeing on hydrants."
Besides being governed by primordial behaviors, Bugsy lists "The Top 20 Reasons Dogs Do Not Use Computers" (courtesy of TopFive.com). My top five favorites are:
5. Too difficult to "mark" every website they visit
4. Three words: Carpal Paw Syndrome
3. Can’t stick their heads out of Windows ’95
2. Can’t heap attacking the screen when they hear "You’ve Got Mail"
1. Butt-sniffing [is] more direct and less deceiving than online chat rooms
On Pizza
Bugsy shares his impressive knowledge of canine anatomy by describing a dog’s ability to detect pizza’s scent via the vomeronasal (Jacobson) organ. This tiny sensory structure is housed in the roof of the mouth just behind the nose and contributes to a characteristic behavior called the flehmen response.
Dogs and other animals exhibit the flehmen response upon detecting substances that stimulate their olfactory (smell) senses, such as pheromone drenched urine. Flehmen distributes the scent across the vomeronasal organ and appears as simultaneous licking, sniffing, and chewing.
I appreciate Bugsy’s instinctual attraction to pizza and frequently strive to maximize my intake of the delicious aroma.
On Spaying and Neutering
Bugsy shares an intriguing perspective that spaying all female dogs would negate the need to neuter male dogs. Such holds true when considering the situation exclusively from a population control perspective.
As a veterinarian, I am always prioritizing the best interest of my patients’ health, so I must mention that intact male dogs are more prone to testicular and prostate tumors and urethral impinging prostate enlargement than neutered male dogs.
Sorry Bugsy, but I think that we must consider both male and female sterilization when it comes to restricting reproduction and prioritizing canine health.
On Vegas
I completely agree with Bugsy’s disdain for Vegas. I just don’t connect with the appeal of "Sin City" (anymore) and the endless options for shenanigans that purportedly stay there.
As most Vegas buildings have "no grass, no windows, and not much room for running…" I feel compelled to make a run for the nearest open field or beach, preferably accompanied by an activity seeking pooch.
On Oprah
Bugsy had the "caninitarian" goal of channeling the power of Oprah to promote better canine health. If only Bugsy had met Oprah and inspired her to proclaim to her devoted legions, "don’t tether your dog, make sure you walk them every day, and feed them whole foods rather than commercial dog food."
As most commercial dog foods contain highly processed, pet grade ingredients deemed unfit for human consumption, I passionately share in Bugsy’s message of whole food feeding as a means of promoting better health.
Why would any pet loving people feed a dog any form of provision that they would not consume themselves? Does Oprah eat her dogs’ food? If they ate Lucky Dog Cuisine, then she’d likely be willing to take a taste.
Thank you, Bugsy, for sharing your insightful perspective. If all humans appreciated your life lessons, the world would be a better place. Dr. Patrick Mahaney
Although Bugsy passed away in 2011, his message lives on through Educating Humans on life from a dog’s point of view, an endearing and amusing collection of life lessons for other dogs and their care-taking humans.
Here are a few of my favorites.
On Car Rides
Bugsy holds the popular canine perspective that car rides are great, since "we [dogs] never know where we are going." Even if the trip’s destination is the veterinarian’s office, the ride is likely reminiscent of other outings until the final turn into the hospital’s parking lot.
As modern life is scheduled with numerous responsibilities dictating every waking moment, I appreciate Bugsy’s openness to uncertainty. The simpler existence most dogs lead permits the outlook that each experience is novel and potentially rewarding.
As part of my efforts to live more simply in 2012, I am striving to embody Bugsy’s positive perspective. I’ll start by taking more spontaneous car outings to the adventuresome places enjoyed by my dog, Cardiff. Perhaps a new beach or hiking trail will serve as our uncharted destination.
On Training
Bugsy hails the merits of early, consistent, and positive reinforcement based training. I agree with and embody Bugsy’s directives with Cardiff well into his adulthood. After all, good behavior strengthens the bond between humans and their canine companions.
Bugsy also notes dogs' ability to direct human behaviors typically benefitting dogs' desires. "When I pace back and forth at 5:30, you know it is dinnertime" is reminiscent of Cardiff’s habit of strategically placing a paw onto the person responsible for provision of his food.
On Computers
Bugsy shows remarkable dedication to writing "while [his] peers are all fetching, running in the park, and peeing on hydrants."
Besides being governed by primordial behaviors, Bugsy lists "The Top 20 Reasons Dogs Do Not Use Computers" (courtesy of TopFive.com). My top five favorites are:
5. Too difficult to "mark" every website they visit
4. Three words: Carpal Paw Syndrome
3. Can’t stick their heads out of Windows ’95
2. Can’t heap attacking the screen when they hear "You’ve Got Mail"
1. Butt-sniffing [is] more direct and less deceiving than online chat rooms
On Pizza
Bugsy shares his impressive knowledge of canine anatomy by describing a dog’s ability to detect pizza’s scent via the vomeronasal (Jacobson) organ. This tiny sensory structure is housed in the roof of the mouth just behind the nose and contributes to a characteristic behavior called the flehmen response.
Dogs and other animals exhibit the flehmen response upon detecting substances that stimulate their olfactory (smell) senses, such as pheromone drenched urine. Flehmen distributes the scent across the vomeronasal organ and appears as simultaneous licking, sniffing, and chewing.
I appreciate Bugsy’s instinctual attraction to pizza and frequently strive to maximize my intake of the delicious aroma.
On Spaying and Neutering
Bugsy shares an intriguing perspective that spaying all female dogs would negate the need to neuter male dogs. Such holds true when considering the situation exclusively from a population control perspective.
As a veterinarian, I am always prioritizing the best interest of my patients’ health, so I must mention that intact male dogs are more prone to testicular and prostate tumors and urethral impinging prostate enlargement than neutered male dogs.
Sorry Bugsy, but I think that we must consider both male and female sterilization when it comes to restricting reproduction and prioritizing canine health.
On Vegas
I completely agree with Bugsy’s disdain for Vegas. I just don’t connect with the appeal of "Sin City" (anymore) and the endless options for shenanigans that purportedly stay there.
As most Vegas buildings have "no grass, no windows, and not much room for running…" I feel compelled to make a run for the nearest open field or beach, preferably accompanied by an activity seeking pooch.
On Oprah
Bugsy had the "caninitarian" goal of channeling the power of Oprah to promote better canine health. If only Bugsy had met Oprah and inspired her to proclaim to her devoted legions, "don’t tether your dog, make sure you walk them every day, and feed them whole foods rather than commercial dog food."
As most commercial dog foods contain highly processed, pet grade ingredients deemed unfit for human consumption, I passionately share in Bugsy’s message of whole food feeding as a means of promoting better health.
Why would any pet loving people feed a dog any form of provision that they would not consume themselves? Does Oprah eat her dogs’ food? If they ate Lucky Dog Cuisine, then she’d likely be willing to take a taste.
Thank you, Bugsy, for sharing your insightful perspective. If all humans appreciated your life lessons, the world would be a better place. Dr. Patrick Mahaney
París Dog Show 2012 - 7- 8 Janvier -
Entre el 7 el 8 de enero de 2012 la Société Canine de l’Ile de France realizará la exposición canina internacional París Dog Show 2012, en el Parc Floral de París, Bois de Vincennes. El evento está dirigido a los amantes de los perros, adiestradores y, al igual que otros años, se convertirá en encuentro más atractivo para que los niños puedan disfrutar observando las distintas razas y sus destrezas.
Las actividades están divididas en competencias y exhibiciones por razas en cinco grupos por día. El sábado 7 los grupos se inician con la presentación de la raza Rottweiller y termina con la variedad Speciale Retriever. El domingo 8 comenzará con la presentación de la raza Speciale Berger Blanc Suisse y termina con los Speciale Chiens Du Tibet.
Cerca de mil perros de diferentes linajes y procedencias estarán mostrando toda su gracia. Para ello hay toda una normativa que contempla aspectos cuyos dueños deben conservar, tal como la hora de llegada y retiro, lugares donde pueden arreglarse, los elementos que pueden usar y los que están prohibidos para hacer ver su pelaje más brillante o acentuar el color, etc.
Por si usted no sabe y quiere presentar a su regalón a esta competencia, sólo debe llevar un simple cepillo para peinarlo. No puede llevar silbato o hacer algún sonido dentro del cuadrilátero, porque queda descalificado. Por cualquier norma que se incumpla, los jueces están autorizados para descalifican al perro y registran en un cuaderno las razones que lo llevaron a tomar la decisión.
Otro de los aspectos que se toman en cuenta, es el estado de salud del perro. Para esto París Dog Show cuenta con un veterinario que tiene autoridad para aceptar o rechazar al competidor. Si su perrita está en etapa de lactancia, no será aceptada aunque usted insista; lo mismo sucede si tiene algún problema en el pelaje o este con falta de movilidad.
Los expositores que residan en el extranjero deberán presentarse ante el Servicio de Aduanas de Francia para la revisión y cumplimiento de los requisitos que exige la internación de animales. Uno de los requisitos es la edad del perrito, que no puede ser inferior a los tres meses de edad y debe tener un certificado de vacunación de un veterinario oficial del país de origen. Los animales de más de un año deberán portar un certificado de vacunación antirrábica autenticada por las autoridades sanitarias de su país.
Uno de los aspectos más destacables de estas competencias es ver la relación de afecto y fidelidad que existe entre amo y perro, que lleva a este último a desplegar toda la gracia, agilidad destreza en silencio, como si estuviera ligado con una conexión invisible a quién le brinda los cuidados protección. Es una bella muestra que enseña a mirar la relación con las mascotas desde otra perspectiva, no sólo de placer personal, sino como un compromiso de ternura mutua.
Para más información http://www.sc-if.org/